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Order NO. D260725
兔抗RAD50多克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D260725-0025 | 25 ul | 现货 |
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| D260725-0100 | 100 ul | 现货 |
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| D260725-0200 | 200 ul | 现货 |
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属性
| Background: | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. (The background information is obtained from official databases and does not represent the product information.) (The background information is obtained from official databases and does not represent the product information.) |
| Applications: | ELISA, WB, IHC |
| Name of antibody: | RAD50 |
| Immunogen: | Synthetic peptide of human RAD50 |
| Full name: | RAD50 double strand break repair protein |
| Synonyms: | NBSLD; RAD502; hRad50 |
| SwissProt: | Q92878 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human thyroid cancer and Human bladder cancer |
| IHC Recommend dilution: | 50-200 |
| WB Predicted band size: | 154 kDa |
| WB Positive control: | 293T, Hela, K562, NIH/3T3 cell lysates |
| WB Recommended dilution: | 1000-5000 |
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