兔抗RNF126多克隆抗体,Anti-RNF126 rabbit polyclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. D260729

兔抗RNF126多克隆抗体

英文名	Anti-RNF126 rabbit polyclonal antibody
相关类别	一抗	储存	冷冻（-20℃）
宿主	Rabbit	反应种属	Human, Mouse, Rat
克隆类型	rabbit polyclonal	抗原	RNF126
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D260729-0025	25 ul	现货	待询价	待询价
D260729-0100	100 ul	现货	待询价	待询价
D260729-0200	200 ul	现货	待询价	待询价

产品描述

概述

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF126 interacts with p21 and RNF126 over-expression increased p21 protein ubiquitination in an E3 ligase activity-dependent manner. RNF126 knockdown induced loss of cell viability in MDA-MB-231 and PC-3 can be partially rescued by depletion of p21. RNF126 stable knockdown in PC3 inhibited tumor growth in SCID mice.

应用

酶联免疫吸附测定（ELISA），免疫印迹（WB），免疫组织化学（IHC）

属性

保存缓冲液	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件	2-8°C
靶点 Uniprot 登记号	Q9BV68
靶点基因 ID	55658
靶点全称	Ring finger protein 126
靶点研究领域	Cell Biology
亚型	Immunogen-specific rabbit IgG

相关文档

Sample Application

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D260729(RNF126 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using D260729(RNF126 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat cells, K562 cells, Primary antibody: D260729(RNF126 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds