Order NO. D260746
兔抗SMAD7多克隆抗体
| 英文名 | Anti-SMAD7 rabbit polyclonal antibody | ||
| 别名 | CRCS3, MADH7, MADH8 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | SMAD7 |
|
|||
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D260746-0025 | 25 ul | 现货 |
|
|
|
| D260746-0100 | 100 ul | 现货 |
|
|
|
| D260746-0200 | 200 ul | 现货 |
|
|
|
产品描述
概述
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | O15105 |
| 靶点基因 ID | 4092 |
| 靶点全称 | SMAD family member 7 |
| 靶点别名 | CRCS3; MADH7; MADH8 |
| 靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
|
||||
Sample Application
