网 站
反 馈
网 站
指 南
Order NO. D261043
兔抗NOTCH3多克隆抗体
英文名 Anti-NOTCH3 rabbit polyclonal antibody
别名 notch 3; IMF2; LMNS; CASIL; CADASIL; CADASIL1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 NOTCH3    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D261043-0025 25 ul 现货
加入购物车
D261043-0100 100 ul 现货
加入购物车
D261043-0200 200 ul 现货
加入购物车

属性

Background: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, WB, IHC
Name of antibody: NOTCH3
Immunogen: Synthetic peptide of human NOTCH3
Full name: notch receptor 3
Synonyms: IMF2; LMNS; CASIL; CADASIL; CADASIL1
SwissProt: Q9UM47
ELISA Recommended dilution: 5000-10000
IHC positive control: Human breast cancer
IHC Recommend dilution: 50-200
WB Predicted band size: 244 kDa
WB Positive control: LOVO, K562, 231 cell lysates
WB Recommended dilution: 1000-5000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D261043(NOTCH3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: LOVO, K562, 231 cell lysates, Primary antibody: D261043(NOTCH3 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 minute
    我的购物车(0) 结算