Order NO. D261087
产品描述
概述
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P37231
|
靶点基因 ID |
5468
|
靶点全称 |
Peroxisome proliferator-activated receptor gamma
|
靶点别名 |
GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Cardiovascular, Stem Cells
|
亚型 |
Immunogen-specific rabbit IgG
|