网 站
反 馈
网 站
指 南
Order NO. D261273
兔抗PRKAA1多克隆抗体
英文名 Anti-PRKAA1 rabbit polyclonal antibody
别名 AMPK; AMPKa1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 PRKAA1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D261273-0025 25 ul 现货
加入购物车
D261273-0100 100 ul 现货
加入购物车
D261273-0200 200 ul 现货
加入购物车
产品描述

概述

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q13131
靶点基因 ID 5562
靶点全称 protein kinase, AMP-activated, alpha 1 catalytic subunit
靶点别名 AMPK; AMPKa1
靶点研究领域 Signal Transduction, Cancer, Metabolism, Cardiovascular, Neuroscience
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D261273(PRKAA1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D261273(PRKAA1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela, Jurkat, NIH/3T3 cell lysates, Primary antibody: D261273(PRKAA1 Antibody) at dilution 1/1350, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 1 minute
    我的购物车(0) 结算