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Order NO. D261451
兔抗SMAD3多克隆抗体
英文名 Anti-SMAD3 rabbit polyclonal antibody
别名 LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 SMAD3
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D261451-0025 25 ul 现货
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D261451-0100 100 ul 现货
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D261451-0200 200 ul 现货
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产品描述

概述

The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P84022
靶点基因 ID 4088
靶点全称 SMAD family member 3
靶点别名 LDS3; mad3; LDS1C; MADH3; JV15-2; hMAD-3; hSMAD3; HSPC193; HsT17436
靶点研究领域 Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D261451(SMAD3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D261451(SMAD3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

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