Order NO. D261539
兔抗CD59多克隆抗体
| 英文名 | Anti-CD59 rabbit polyclonal antibody | ||
| 别名 | 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 克隆类型 | rabbit polyclonal | 抗原 | CD59 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D261539-0025 | 25 ul | 现货 |
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| D261539-0100 | 100 ul | 现货 |
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| D261539-0200 | 200 ul | 现货 |
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产品描述
概述
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P13987 |
| 靶点基因 ID | 966 |
| 靶点全称 | CD59 molecule, complement regulatory protein |
| 靶点别名 | 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20 |
| 靶点研究领域 | Signal Transduction, Cardiovascular, Immunology, Stem Cells |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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