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Order NO. D261586
兔抗CDK12多克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D261586-0025 | 25 ul | 现货 |
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| D261586-0100 | 100 ul | 现货 |
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| D261586-0200 | 200 ul | 现货 |
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产品描述
概述
Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q9NYV4 |
| 靶点基因 ID | 51755 |
| 靶点全称 | cyclin dependent kinase 12 |
| 靶点别名 | CRK7; CRKR; CRKRS |
| 靶点研究领域 | Signal Transduction |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
Sample Application
