兔抗EP300多克隆抗体,Anti-EP300 rabbit polyclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. D261648

兔抗EP300多克隆抗体

英文名	Anti-EP300 rabbit polyclonal antibody
别名	p300; KAT3B; RSTS2
相关类别	一抗	储存	冷冻（-20℃）
宿主	Rabbit	反应种属	Human, Mouse
克隆类型	rabbit polyclonal	抗原	EP300
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D261648-0025	25 ul	现货	待询价	待询价
D261648-0100	100 ul	现货	待询价	待询价
D261648-0200	200 ul	现货	待询价	待询价

产品描述

概述

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

应用

酶联免疫吸附测定（ELISA），免疫组织化学（IHC）

属性

保存缓冲液	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件	2-8°C
靶点 Uniprot 登记号	Q09472
靶点基因 ID	2033
靶点全称	E1A binding protein p300
靶点别名	p300; KAT3B; RSTS2
靶点研究领域	Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Signal Transduction
亚型	Immunogen-specific rabbit IgG

相关文档

Sample Application

The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using D261648(EP300 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using D261648(EP300 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)