Order NO. D261648
兔抗EP300多克隆抗体
| 英文名 | Anti-EP300 rabbit polyclonal antibody | ||
| 别名 | p300; KAT3B; RSTS2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 克隆类型 | rabbit polyclonal | 抗原 | EP300 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D261648-0025 | 25 ul | 现货 |
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| D261648-0100 | 100 ul | 现货 |
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| D261648-0200 | 200 ul | 现货 |
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产品描述
概述
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q09472 |
| 靶点基因 ID | 2033 |
| 靶点全称 | E1A binding protein p300 |
| 靶点别名 | p300; KAT3B; RSTS2 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Signal Transduction |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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