Order NO. D261914
产品描述
概述
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q16584
|
靶点基因 ID |
4296
|
靶点全称 |
mitogen-activated protein kinase kinase kinase 11
|
靶点别名 |
MLK3; PTK1; SPRK; MLK-3; MEKK11
|
靶点研究领域 |
Signal Transduction
|
亚型 |
Immunogen-specific rabbit IgG
|