Order NO. D262042
产品描述
概述
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q86YN6
|
靶点基因 ID |
133522
|
靶点全称 |
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
|
靶点别名 |
PERC; ERRL1; PGC1B; PGC-1(beta)
|
靶点研究领域 |
Metabolism, Epigenetics and Nuclear Signaling, Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|