Order NO. D262448
兔抗UCP2多克隆抗体
| 英文名 | Anti-UCP2 rabbit polyclonal antibody | ||
| 别名 | UCPH; BMIQ4; SLC25A8 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
| 抗原 | UCP2 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D262448-0025 | 25 ul | 现货 |
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| D262448-0100 | 100 ul | 现货 |
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| D262448-0200 | 200 ul | 现货 |
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属性
| WB Recommended dilution: | 200-1000 |
| WB Positive control: | Mouse liver tissue lysate |
| WB Predicted band size: | 33 kDa |
| IHC Recommend dilution: | 25-100 |
| IHC positive control: | Human breast cancer and Human colorectal cancer |
| ELISA Recommended dilution: | 5000-10000 |
| SwissProt: | P55851 |
| Synonyms: | UCPH; BMIQ4; SLC25A8 |
| Full name: | uncoupling protein 2 |
| Immunogen: | Synthetic peptide of human UCP2 |
| Name of antibody: | UCP2 |
| Applications: | ELISA, WB, IHC |
| Background: | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. |
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