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Order NO. D262456
兔抗CHD3多克隆抗体
英文名 Anti-CHD3 rabbit polyclonal antibody
别名 chromodomain helicase DNA binding protein 3; ZFH; Mi-2a; Mi2-ALPHA
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 CHD3
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D262456-0025 25 ul 现货
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D262456-0100 100 ul 现货
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D262456-0200 200 ul 现货
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产品描述

概述

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q12873
靶点基因 ID 1107
靶点全称 chromodomain helicase DNA binding protein 3
靶点别名 ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA
靶点研究领域 Epigenetics and Nuclear Signaling, Immunology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D262456(CHD3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using D262456(CHD3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)