Order NO. D262656
产品描述
概述
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P20823
|
靶点基因 ID |
6927
|
靶点全称 |
HNF1 homeobox A
|
靶点别名 |
HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20
|
靶点研究领域 |
Epigenetics and Nuclear Signaling
|
亚型 |
Immunogen-specific rabbit IgG
|