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Order NO. D262763
兔抗COX7A2L多克隆抗体
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D262763-0025 | 25 ul | 现货 |
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D262763-0100 | 100 ul | 现货 |
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D262763-0200 | 200 ul | 现货 |
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属性
Background: | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |
Applications: | ELISA, IHC |
Name of antibody: | COX7A2L |
Immunogen: | Synthetic peptide of human COX7A2L |
Full name: | cytochrome c oxidase subunit 7A2 like |
Synonyms: | EB1; SCAF1; SCAFI; SIG81; COX7AR; COX7RP |
SwissProt: | O14548 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human prostate cancer |
IHC Recommend dilution: | 25-100 |