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Order NO. D262975
兔抗TGFB1多克隆抗体
英文名 Anti-TGFB1 rabbit polyclonal antibody
别名 CED; LAP; DPD1; TGFB; TGFbeta
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 TGFB1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D262975-0025 25 ul 现货
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D262975-0100 100 ul 现货
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D262975-0200 200 ul 现货
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属性

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, IHC
Name of antibody: TGFB1
Immunogen: Synthetic peptide of human TGFB1
Full name: transforming growth factor beta 1
Synonyms: CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1
SwissProt: P01137
ELISA Recommended dilution: 5000-10000
IHC positive control: Human liver cancer
IHC Recommend dilution: 50-200
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D262975(TGFB1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

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