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Order NO. D263180
兔抗XRN1多克隆抗体
英文名 Anti-XRN1 rabbit polyclonal antibody
别名 5'-3' exoribonuclease 1; SEP1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 XRN1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D263180-0025 25 ul 现货
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D263180-0100 100 ul 现货
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D263180-0200 200 ul 现货
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属性

Background: This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.
Applications: ELISA, WB, IHC
Name of antibody: XRN1
Immunogen: Synthetic peptide of human XRN1
Full name: 5'-3' exoribonuclease 1
Synonyms: SEP1
SwissProt: Q8IZH2
ELISA Recommended dilution: 5000-10000
IHC positive control: Human lung cancer and Human bladder cancer
IHC Recommend dilution: 50-200
WB Predicted band size: 194 kDa
WB Positive control: 293T and Hela cell lysates
WB Recommended dilution: 1000-5000
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using D263180(XRN1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human bladder cancer tissue using D263180(XRN1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T and Hela cell lysates, Primary antibody: D263180(XRN1 Antibody) at dilution 1/1000, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 10 seconds
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