Order NO. D263697
兔抗FBXO32多克隆抗体
英文名 | Anti-FBXO32 rabbit polyclonal antibody | ||
别名 | Fbx32; MAFbx | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
抗原 | FBXO32 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D263697-0025 | 25 ul | 现货 |
|
||
D263697-0100 | 100 ul | 现货 |
|
||
D263697-0200 | 200 ul | 现货 |
|
属性
Background: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: | ELISA, IHC |
Name of antibody: | FBXO32 |
Immunogen: | Synthetic peptide of human FBXO32 |
Full name: | F-box protein 32 |
Synonyms: | Fbx32; MAFbx |
SwissProt: | Q969P5 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human skeletal muscle |
IHC Recommend dilution: | 50-200 |