Order NO. D264265
产品描述
概述
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P42263
|
靶点基因 ID |
2892
|
靶点全称 |
glutamate ionotropic receptor AMPA type subunit 3
|
靶点别名 |
GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3
|
靶点研究领域 |
Signal Transduction, Neuroscience
|
亚型 |
Immunogen-specific rabbit IgG
|