网 站
反 馈
网 站
指 南
Order NO. D264329
兔抗TJP1多克隆抗体
英文名 Anti-TJP1 rabbit polyclonal antibody
别名 tight junction protein 1; ZO-1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 TJP1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D264329-0025 25 ul 现货
加入购物车
D264329-0100 100 ul 现货
加入购物车
D264329-0200 200 ul 现货
加入购物车

属性

Background: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, IHC
Name of antibody: TJP1
Immunogen: Synthetic peptide of human TJP1
Full name: tight junction protein 1
Synonyms: ZO-1
SwissProt: Q07157
ELISA Recommended dilution: 5000-10000
IHC positive control: Human liver cancer
IHC Recommend dilution: 50-200
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using D264329(TJP1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

    我的购物车(0) 结算