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Order NO. D264329
兔抗TJP1多克隆抗体
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英文名 | Anti-TJP1 rabbit polyclonal antibody | ||
别名 | tight junction protein 1; ZO-1 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit polyclonal |
抗原 | TJP1 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D264329-0025 | 25 ul | 现货 |
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D264329-0100 | 100 ul | 现货 |
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D264329-0200 | 200 ul | 现货 |
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属性
Background: | This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017] (The background information is obtained from official databases and does not represent the product information.) |
Applications: | ELISA, IHC |
Name of antibody: | TJP1 |
Immunogen: | Synthetic peptide of human TJP1 |
Full name: | tight junction protein 1 |
Synonyms: | ZO-1 |
SwissProt: | Q07157 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human liver cancer |
IHC Recommend dilution: | 50-200 |