Order NO. D264377
兔抗ALKBH5多克隆抗体
| 英文名 | Anti-ALKBH5 rabbit polyclonal antibody | ||
| 别名 | alkB homolog 5, RNA demethylase; ABH5; OFOXD; OFOXD1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | ALKBH5 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D264377-0025 | 25 ul | 现货 |
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| D264377-0100 | 100 ul | 现货 |
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| D264377-0200 | 200 ul | 现货 |
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产品描述
概述
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro). Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells.
应用
酶联免疫吸附测定（ELISA），免疫印迹（WB）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q6P6C2 |
| 靶点基因 ID | 54890 |
| 靶点全称 | alkB homolog 5, RNA demethylase |
| 靶点别名 | ABH5; OFOXD; OFOXD1 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
