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Order NO. D264624
兔抗MAP4K4多克隆抗体
英文名 Anti-MAP4K4 rabbit polyclonal antibody
别名 mitogen-activated protein kinase kinase kinase kinase 4; HGK; NIK; MEKKK4; FLH21957; HEL-S-31
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 MAP4K4
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D264624-0025 25 ul 现货
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D264624-0100 100 ul 现货
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D264624-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 O95819
靶点基因 ID 9448
靶点全称 mitogen-activated protein kinase kinase kinase kinase 4
靶点别名 HGK; NIK; MEKKK4; FLH21957; HEL-S-31
靶点研究领域 Signal Transduction
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Raji cell lysate, Primary antibody: D264624(MAP4K4 Antibody) at dilution 1/800, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 5 seconds