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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D264624-0025 | 25 ul | 现货 |
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D264624-0100 | 100 ul | 现货 |
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D264624-0200 | 200 ul | 现货 |
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概述
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | O95819 |
靶点基因 ID | 9448 |
靶点全称 | mitogen-activated protein kinase kinase kinase kinase 4 |
靶点别名 | HGK; NIK; MEKKK4; FLH21957; HEL-S-31 |
靶点研究领域 | Signal Transduction |
亚型 | Immunogen-specific rabbit IgG |

