Order NO. D290110
兔抗ATF2 (phospho-Thr71)单克隆抗体
| 英文名 | Anti-ATF2 (phospho-Thr71) rabbit monoclonal antibody | ||
| 别名 | activating transcription factor 2; HB16; CREB2; TREB7; CREB-2; CRE-BP1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | ATF2 (phospho-Thr71) | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290110-0050 | 50 ul | 预计5日内发货 |
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| D290110-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] |
| Applications: | WB, IF |
| Name of antibody: | ATF2 (phospho-Thr71) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2 |
| Full name: | activating transcription factor 2 |
| Synonyms: | HB16; CREB2; TREB7; CREB-2; CRE-BP1 |
| SwissProt: | P15336 |
| WB Predicted band size: | 55 kDa |
| WB Positive control: | 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | U87-MG cells |
| IF Recommended dilution: | 50-200 |
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