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Order NO. D290149
兔抗BAP1单克隆抗体
英文名 Anti-BAP1 rabbit monoclonal antibody
别名 BRCA1 associated protein 1; UBM2; UVM2; KURIS; TPDS1; UCHL2; hucep-6; HUCEP-13
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 BAP1    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D290149-0050 50 ul 预计5日内发货
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D290149-0100 100 ul 预计5日内发货
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属性

Background: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
Applications: WB
Name of antibody: BAP1
Immunogen: Fusion protein of human BAP1
Full name: BRCA1 associated protein 1
Synonyms: UBM2; UVM2; KURIS; TPDS1; UCHL2; hucep-6; HUCEP-13
SwissProt: Q92560
WB Predicted band size: 80 kDa
WB Positive control: Hela, A549, HL-60, U2OS lysates
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-4: Hela, A549, HL-60, U2OS lysates, Primary antibody: D290149(BAP1 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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