
Order NO. D290149
兔抗BAP1单克隆抗体


英文名 | Anti-BAP1 rabbit monoclonal antibody | ||
别名 | BRCA1 associated protein 1; UBM2; UVM2; KURIS; TPDS1; UCHL2; hucep-6; HUCEP-13 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | BAP1 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D290149-0050 | 50 ul | 预计5日内发货 |
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D290149-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013] |
Applications: | WB |
Name of antibody: | BAP1 |
Immunogen: | Fusion protein of human BAP1 |
Full name: | BRCA1 associated protein 1 |
Synonyms: | UBM2; UVM2; KURIS; TPDS1; UCHL2; hucep-6; HUCEP-13 |
SwissProt: | Q92560 |
WB Predicted band size: | 80 kDa |
WB Positive control: | Hela, A549, HL-60, U2OS lysates |
WB Recommended dilution: | 500-2000 |