Order NO. D290204
兔抗CASP1单克隆抗体
| 英文名 | Anti-CASP1 rabbit monoclonal antibody | ||
| 别名 | caspase 1; ICE; P45; IL1BC | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | CASP1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290204-0050 | 50 ul | 预计5日内发货 |
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| D290204-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012] |
| Applications: | WB |
| Name of antibody: | CASP1 |
| Immunogen: | Fusion protein of human CASP1 |
| Full name: | caspase 1 |
| Synonyms: | ICE; P45; IL1BC |
| SwissProt: | P29466 |
| WB Predicted band size: | 45 kDa |
| WB Positive control: | Hela lysate |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
