Order NO. D290229
兔抗CCND1单克隆抗体
| 英文名 | Anti-CCND1 rabbit monoclonal antibody | ||
| 别名 | cyclin D1; BCL1; PRAD1; U21B31; D11S287E | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | CCND1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290229-0050 | 50 ul | 预计5日内发货 |
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| D290229-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers. [provided by RefSeq, Dec 2019] |
| Applications: | WB |
| Name of antibody: | CCND1 |
| Immunogen: | Synthetic peptide of human CCND1 |
| Full name: | cyclin D1 |
| Synonyms: | BCL1; PRAD1; U21B31; D11S287E |
| SwissProt: | P24385 |
| WB Predicted band size: | 34 kDa |
| WB Positive control: | NIH/3T3, C6 lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
