Order NO. D290258
兔抗CDC42单克隆抗体
英文名 | Anti-CDC42 rabbit monoclonal antibody | ||
别名 | cell division cycle 42; TKS; G25K; CDC42Hs | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | CDC42 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D290258-0050 | 50 ul | 现货 |
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D290258-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013] |
Applications: | WB |
Name of antibody: | CDC42 |
Immunogen: | Synthetic peptide of human CDC42 |
Full name: | cell division cycle 42 |
Synonyms: | TKS; G25K; CDC42Hs |
SwissProt: | P60953 |
WB Predicted band size: | 21 kDa |
WB Positive control: | Hela, Rat brain, Mouse brain, Jurkat, Mouse spleen lysates |
WB Recommended dilution: | 500-2000 |