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Order NO. D290258
兔抗CDC42单克隆抗体
英文名 Anti-CDC42 rabbit monoclonal antibody
别名 cell division cycle 42; TKS; G25K; CDC42Hs
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 CDC42    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D290258-0050 50 ul 现货
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D290258-0100 100 ul 预计5日内发货
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属性

Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Applications: WB
Name of antibody: CDC42
Immunogen: Synthetic peptide of human CDC42
Full name: cell division cycle 42
Synonyms: TKS; G25K; CDC42Hs
SwissProt: P60953
WB Predicted band size: 21 kDa
WB Positive control: Hela, Rat brain, Mouse brain, Jurkat, Mouse spleen lysates
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane 1-5: Hela, Rat brain, Mouse brain, Jurkat, Mouse spleen lysates, Primary antibody: D290258(CDC42 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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