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Order NO. D290262
兔抗CDH1 (phospho-Ser838/Ser840)单克隆抗体
英文名 Anti-CDH1 (phospho-Ser838/Ser840) rabbit monoclonal antibody
别名 cadherin 1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 CDH1 (phospho-Ser838/Ser840)    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D290262-0050 50 ul 预计5日内发货
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D290262-0100 100 ul 预计5日内发货
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属性

Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
Applications: WB, IHC
Name of antibody: CDH1 (phospho-Ser838/Ser840)
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser838/Ser840 of human CDH1
Full name: cadherin 1
Synonyms: UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
SwissProt: P12830
IHC positive control: Human breast cancer
IHC Recommend dilution: 50-100
WB Predicted band size: 97 kDa
WB Positive control: HepG2, U2OS, U251, LNCAP, 3T3, Mouse brain lysates
WB Recommended dilution: 500-2000
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using D290262(CDH1 (phospho-Ser838/Ser840) Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-6: HepG2, U2OS, U251, LNCAP, 3T3, Mouse brain lysates, Primary antibody: D290262(CDH1 (phospho-Ser838/Ser840) Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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