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Order NO. D290264
兔抗CDH10单克隆抗体
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英文名 | Anti-CDH10 rabbit monoclonal antibody | ||
别名 | cadherin 10 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | CDH10 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D290264-0050 | 50 ul | 预计5日内发货 |
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D290264-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015] |
Applications: | WB |
Name of antibody: | CDH10 |
Immunogen: | Synthetic peptide of human CDH10 |
Full name: | cadherin 10 |
SwissProt: | Q9Y6N8 |
WB Predicted band size: | 88 kDa |
WB Positive control: | U2OS, C6, MEF lysates |
WB Recommended dilution: | 500-2000 |