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Order NO. D290264
兔抗CDH10单克隆抗体
英文名 Anti-CDH10 rabbit monoclonal antibody
别名 cadherin 10
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 CDH10    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D290264-0050 50 ul 预计5日内发货
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D290264-0100 100 ul 预计5日内发货
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属性

Background: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015]
Applications: WB
Name of antibody: CDH10
Immunogen: Synthetic peptide of human CDH10
Full name: cadherin 10
SwissProt: Q9Y6N8
WB Predicted band size: 88 kDa
WB Positive control: U2OS, C6, MEF lysates
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-3: U2OS, C6, MEF lysates, Primary antibody: D290264(CDH10 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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