Order NO. D290276
兔抗CDK6单克隆抗体
| 英文名 | Anti-CDK6 rabbit monoclonal antibody | ||
| 别名 | cyclin dependent kinase 6; MCPH12; PLSTIRE | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | CDK6 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290276-0050 | 50 ul | 预计5日内发货 |
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| D290276-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017] |
| Applications: | WB |
| Name of antibody: | CDK6 |
| Immunogen: | Synthetic peptide of human CDK6 |
| Full name: | cyclin dependent kinase 6 |
| Synonyms: | MCPH12; PLSTIRE |
| SwissProt: | Q00534 |
| WB Predicted band size: | 37 kDa |
| WB Positive control: | K562, Hela lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
