Order NO. D290319
兔抗COL1A1单克隆抗体
| 英文名 | Anti-COL1A1 rabbit monoclonal antibody | ||
| 别名 | collagen type I alpha 1 chain; OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | COL1A1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290319-0050 | 50 ul | 预计5日内发货 |
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| D290319-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
| Applications: | WB, IF |
| Name of antibody: | COL1A1 |
| Immunogen: | Fusion protein of human COL1A1 |
| Full name: | collagen type I alpha 1 chain |
| Synonyms: | OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1 |
| SwissProt: | P02452 |
| WB Predicted band size: | 139 kDa |
| WB Positive control: | A549, HL-60, U2OS lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution: | 50-200 |
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