Order NO. D290472
兔抗ENO1/ENO2/ENO3单克隆抗体
| 英文名 | Anti-ENO1/ENO2/ENO3 rabbit monoclonal antibody | ||
| 别名 | enolase 1/2/3; NNE; PPH; MPB1; ENO1L1; ENO1-IT1; HEL-S-17; NSE; HEL-S-279; MSE; GSD13 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | ENO1/ENO2/ENO3 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290472-0050 | 50 ul | 预计5日内发货 |
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| D290472-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The ENO1 gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. The ENO2 gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. The ENO3 gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Applications: | WB |
| Name of antibody: | ENO1/ENO2/ENO3 |
| Immunogen: | Fusion protein of human ENO1 |
| Full name: | enolase 1/2/3 |
| Synonyms: | NNE; PPH; MPB1; ENO1L1; ENO1-IT1; HEL-S-17; NSE; HEL-S-279; MSE; GSD13 |
| SwissProt: | P06733 |
| WB Predicted band size: | 47 kDa |
| WB Positive control: | Rat brain, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
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