Order NO. D290484
兔抗ERBB2 (phospho-Tyr1248/Tyr1173)单克隆抗体
| 英文名 | Anti-ERBB2 (phospho-Tyr1248/Tyr1173) rabbit monoclonal antibody | ||
| 别名 | erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; VSCN2; MLN 19; MLN-19; c-ERB2; c-ERB-2; HER-2/neu; p185(erbB2 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | ERBB2 (phospho-Tyr1248/Tyr1173) | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290484-0050 | 50 ul | 预计5日内发货 |
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| D290484-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008] |
| Applications: | WB |
| Name of antibody: | ERBB2 (phospho-Tyr1248/Tyr1173) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ERBB2 |
| Full name: | erb-b2 receptor tyrosine kinase 2 |
| Synonyms: | NEU; NGL; HER2; TKR1; CD340; HER-2; VSCN2; MLN 19; MLN-19; c-ERB2; c-ERB-2; HER-2/neu; p185(erbB2) |
| SwissProt: | P04626 |
| WB Predicted band size: | 138 kDa |
| WB Positive control: | Hela lysate |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
