Order NO. D290884
兔抗MAPK1/MAPK3单克隆抗体
| 英文名 | Anti-MAPK1/MAPK3 rabbit monoclonal antibody | ||
| 别名 | mitogen-activated protein kinase 1/3; ERK; p38; p40; p41; ERK2; ERT1; NS13; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK;E | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | MAPK1/MAPK3 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290884-0050 | 50 ul | 预计5日内发货 |
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| D290884-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The MAPK1 gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. The protein encoded by the MAPK3 gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. |
| Applications: | WB, IF |
| Name of antibody: | MAPK1/MAPK3 |
| Immunogen: | Fusion protein of human MAPK1/MAPK3 |
| Full name: | mitogen-activated protein kinase 1/3 |
| Synonyms: | ERK; p38; p40; p41; ERK2; ERT1; NS13; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK |
| SwissProt: | P28482/P27361 |
| WB Predicted band size: | 41/43 kDa |
| WB Positive control: | K562, Rat brain, C6, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | K562 cells |
| IF Recommended dilution: | 50-200 |
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