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Order NO. D290910
兔抗MCM2 (phospho-Ser108)单克隆抗体
英文名 Anti-MCM2 (phospho-Ser108) rabbit monoclonal antibody
别名 minichromosome maintenance complex component 2; BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 MCM2 (phospho-Ser108)    
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D290910-0050 50 ul 预计5日内发货 待询价 待询价
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D290910-0100 100 ul 预计5日内发货 待询价 待询价
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属性

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
Applications: WB, IF
Name of antibody: MCM2 (phospho-Ser108)
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser108 of human MCM2
Full name: minichromosome maintenance complex component 2
Synonyms: BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN
SwissProt: P49736
WB Predicted band size: 102 kDa
WB Positive control: K562, 3T3, Hela, Rat spleen lysates
WB Recommended dilution: 500-2000
IF Positive control: Hela cells
IF Recommended dilution: 50-200
相关文档
Sample Application

  • The image is immunofluorescence of Hela cells using D290910(MCM2 (phospho-Ser108) Antibody) at dilution 1/50 (green). Blue: DAPI

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-4: K562, 3T3, Hela, Rat spleen lysates, Primary antibody: D290910(MCM2 (phospho-Ser108) Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes