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Order NO. D290910
兔抗MCM2 (phospho-Ser108)单克隆抗体
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D290910-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 |
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D290910-0100 | 100 ul | 预计5日内发货 | 待询价 | 待询价 |
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属性
Background: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] |
Applications: | WB, IF |
Name of antibody: | MCM2 (phospho-Ser108) |
Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Ser108 of human MCM2 |
Full name: | minichromosome maintenance complex component 2 |
Synonyms: | BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN |
SwissProt: | P49736 |
WB Predicted band size: | 102 kDa |
WB Positive control: | K562, 3T3, Hela, Rat spleen lysates |
WB Recommended dilution: | 500-2000 |
IF Positive control: | Hela cells |
IF Recommended dilution: | 50-200 |
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