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Order NO. D291121
兔抗PDHA1单克隆抗体
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英文名 | Anti-PDHA1 rabbit monoclonal antibody | ||
别名 | pyruvate dehydrogenase E1 subunit alpha 1; PDHA; PDHAD; PHE1A; E1alpha; PDHCE1A | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | PDHA1 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291121-0050 | 50 ul | 现货 |
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D291121-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
Applications: | WB, IF |
Name of antibody: | PDHA1 |
Immunogen: | Synthetic peptide of human PDHA1 |
Full name: | pyruvate dehydrogenase E1 subunit alpha 1 |
Synonyms: | PDHA; PDHAD; PHE1A; E1alpha; PDHCE1A |
SwissProt: | P08559 |
WB Predicted band size: | 43 kDa |
WB Positive control: | C6, 3T3 lysates |
WB Recommended dilution: | 500-2000 |
IF Positive control: | Hela cells |
IF Recommended dilution: | 50-200 |