
Order NO. D291195
兔抗PPP1CA单克隆抗体



英文名 | Anti-PPP1CA rabbit monoclonal antibody | ||
别名 | protein phosphatase 1 catalytic subunit alpha; PP1A; PP-1A; PPP1A; PP1alpha | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | PPP1CA | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291195-0050 | 50 ul | 预计5日内发货 |
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D291195-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020] |
Applications: | WB, IHC |
Name of antibody: | PPP1CA |
Immunogen: | Synthetic peptide of human PPP1CA |
Full name: | protein phosphatase 1 catalytic subunit alpha |
Synonyms: | PP1A; PP-1A; PPP1A; PP1alpha |
SwissProt: | P62136 |
IHC positive control: | mouse colon |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 38 kDa |
WB Positive control: | K562, Rat brain, Mouse kidney, RAW264.7 lysates |
WB Recommended dilution: | 500-2000 |