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Order NO. D291195
兔抗PPP1CA单克隆抗体
英文名 Anti-PPP1CA rabbit monoclonal antibody
别名 protein phosphatase 1 catalytic subunit alpha; PP1A; PP-1A; PPP1A; PP1alpha
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 PPP1CA    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D291195-0050 50 ul 预计5日内发货
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D291195-0100 100 ul 预计5日内发货
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属性

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020]
Applications: WB, IHC
Name of antibody: PPP1CA
Immunogen: Synthetic peptide of human PPP1CA
Full name: protein phosphatase 1 catalytic subunit alpha
Synonyms: PP1A; PP-1A; PPP1A; PP1alpha
SwissProt: P62136
IHC positive control: mouse colon
IHC Recommend dilution: 50-100
WB Predicted band size: 38 kDa
WB Positive control: K562, Rat brain, Mouse kidney, RAW264.7 lysates
WB Recommended dilution: 500-2000
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Sample Application

  • The image is immunohistochemistry of paraffin-embedded mouse colon tissue using D291195(PPP1CA Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-4: K562, Rat brain, Mouse kidney, RAW264.7 lysates, Primary antibody: D291195(PPP1CA Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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