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Order NO. D291216
兔抗PRKAA2单克隆抗体
英文名 Anti-PRKAA2 rabbit monoclonal antibody
别名 protein kinase AMP-activated catalytic subunit alpha 2; AMPK; AMPK2; PRKAA; AMPKa2
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 PRKAA2    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D291216-0050 50 ul 预计5日内发货
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D291216-0100 100 ul 预计5日内发货
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属性

Background: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Applications: WB
Name of antibody: PRKAA2
Immunogen: Fusion protein of human PRKAA2
Full name: protein kinase AMP-activated catalytic subunit alpha 2
Synonyms: AMPK; AMPK2; PRKAA; AMPKa2
SwissProt: P54646
WB Predicted band size: 62 kDa
WB Positive control: C6, Hela lysates
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-2: C6, Hela lysates, Primary antibody: D291216(PRKAA2 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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