Order NO. D291228
兔抗PRKCG (phospho-Thr514)单克隆抗体
| 英文名 | Anti-PRKCG (phospho-Thr514) rabbit monoclonal antibody | ||
| 别名 | protein kinase C gamma; PKCC; PKCG; SCA14; PKCI(3); PKCgamma; PKC-gamma | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | PRKCG (phospho-Thr514) | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291228-0050 | 50 ul | 预计5日内发货 |
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| D291228-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Applications: | WB, IHC |
| Name of antibody: | PRKCG (phospho-Thr514) |
| Immunogen: | Synthetic peptide of human PRKCG |
| Full name: | protein kinase C gamma |
| Synonyms: | PKCC; PKCG; SCA14; PKCI(3); PKCgamma; PKC-gamma |
| SwissProt: | P05129 |
| IHC positive control: | Human Brain |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 78 kDa |
| WB Positive control: | C6, Hela, Mouse brain lysates |
| WB Recommended dilution: | 500-2000 |
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