Order NO. D291258
兔抗PTBP1单克隆抗体
| 英文名 | Anti-PTBP1 rabbit monoclonal antibody | ||
| 别名 | polypyrimidine tract binding protein 1; PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Hamster |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | PTBP1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291258-0050 | 50 ul | 预计5日内发货 |
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| D291258-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Applications: | WB, IHC |
| Name of antibody: | PTBP1 |
| Immunogen: | Synthetic peptide of human PTBP1 |
| Full name: | polypyrimidine tract binding protein 1 |
| Synonyms: | PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I |
| SwissProt: | P26599 |
| IHC positive control: | Human tonsil |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 57 kDa |
| WB Positive control: | Hela, CHO-K1, Ramos, 3T3 lysates |
| WB Recommended dilution: | 500-2000 |
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