Order NO. D291268
兔抗PTK2B单克隆抗体
| 英文名 | Anti-PTK2B rabbit monoclonal antibody | ||
| 别名 | protein tyrosine kinase 2 beta; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | PTK2B | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291268-0050 | 50 ul | 预计5日内发货 |
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| D291268-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Applications: | WB, IHC |
| Name of antibody: | PTK2B |
| Immunogen: | Synthetic peptide of human PTK2B |
| Full name: | protein tyrosine kinase 2 beta |
| Synonyms: | PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK |
| SwissProt: | Q14289 |
| IHC positive control: | Human tonsil |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 116 kDa |
| WB Positive control: | A549, HL-60, U2OS lysates |
| WB Recommended dilution: | 500-2000 |
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