Order NO. D291277
兔抗PTTG1单克隆抗体
| 英文名 | Anti-PTTG1 rabbit monoclonal antibody | ||
| 别名 | PTTG1 regulator of sister chromatid separation, securin; EAP1; PTTG; ECRAR; HPTTG; TUTR1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | PTTG1 | ||
|
|||
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291277-0050 | 50 ul | 预计5日内发货 |
|
|
|
| D291277-0100 | 100 ul | 预计5日内发货 |
|
|
|
属性
| Background: | The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] |
| Applications: | WB, IHC |
| Name of antibody: | PTTG1 |
| Immunogen: | Synthetic peptide of human PTTG1 |
| Full name: | PTTG1 regulator of sister chromatid separation, securin |
| Synonyms: | EAP1; PTTG; ECRAR; HPTTG; TUTR1 |
| SwissProt: | O95997 |
| IHC positive control: | Human tonsil |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 22 kDa |
| WB Positive control: | K562, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
|
||||
Sample Application
