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Order NO. D291300
兔抗RAD50单克隆抗体
英文名 Anti-RAD50 rabbit monoclonal antibody
别名 RAD50 double strand break repair protein; NBSLD; RAD502; hRad50
相关类别 一抗 储存 冷冻（-20℃）
宿主 Rabbit 反应种属 Human
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 RAD50    
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
D291300-0050 50 ul 预计5日内发货 待询价 待询价
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D291300-0100 100 ul 预计5日内发货 待询价 待询价
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属性

Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
Applications: WB, IHC
Name of antibody: RAD50
Immunogen: Fusion protein of human RAD50
Full name: RAD50 double strand break repair protein
Synonyms: NBSLD; RAD502; hRad50
SwissProt: Q92878
IHC positive control: Human cholangiocarcinoma
IHC Recommend dilution: 50-100
WB Predicted band size: 154 kDa
WB Positive control: Hela, A549, HL-60 lysates
WB Recommended dilution: 500-2000
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human cholangiocarcinoma tissue using D291300(RAD50 Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-3: Hela, A549, HL-60 lysates, Primary antibody: D291300(RAD50 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes