Order NO. D291301
兔抗RAD51单克隆抗体
英文名 | Anti-RAD51 rabbit monoclonal antibody | ||
别名 | RAD51 recombinase; RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | RAD51 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291301-0050 | 50 ul | 预计5日内发货 |
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D291301-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] |
Applications: | WB, IF |
Name of antibody: | RAD51 |
Immunogen: | Synthetic peptide of human RAD51 |
Full name: | RAD51 recombinase |
Synonyms: | RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930 |
SwissProt: | Q06609 |
WB Predicted band size: | 37 kDa |
WB Positive control: | C6, 3T3, Hela lysates |
WB Recommended dilution: | 500-2000 |
IF Positive control: | Jurkat cells |
IF Recommended dilution: | 50-200 |