Order NO. D291304
兔抗RAF1单克隆抗体
| 英文名 | Anti-RAF1 rabbit monoclonal antibody | ||
| 别名 | Raf-1 proto-oncogene, serine/threonine kinase; NS5; CRAF; Raf-1; c-Raf; CMD1NN | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | RAF1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291304-0050 | 50 ul | 预计5日内发货 |
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| D291304-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008] |
| Applications: | WB, IF |
| Name of antibody: | RAF1 |
| Immunogen: | Synthetic peptide of human RAF1 |
| Full name: | Raf-1 proto-oncogene, serine/threonine kinase |
| Synonyms: | NS5; CRAF; Raf-1; c-Raf; CMD1NN |
| SwissProt: | P04049 |
| WB Predicted band size: | 73 kDa |
| WB Positive control: | C6, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | MCF-7 cells |
| IF Recommended dilution: | 50-200 |
相关文档
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Sample Application
