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Order NO. D291323
兔抗RB1 (phospho-Thr356)单克隆抗体
英文名 Anti-RB1 (phospho-Thr356) rabbit monoclonal antibody
别名 RB transcriptional corepressor 1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
相关类别 一抗 储存 冷冻（-20℃）
宿主 Rabbit 反应种属 Human, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 RB1 (phospho-Thr356)    
编 号 包装 库存 目录价（￥） 您的价格（￥） 数 量
D291323-0050 50 ul 预计5日内发货
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D291323-0100 100 ul 预计5日内发货
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属性

Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Applications: WB, IHC
Name of antibody: RB1 (phospho-Thr356)
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr356 of human RB1
Full name: RB transcriptional corepressor 1
Synonyms: RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
SwissProt: P06400
IHC positive control: Human tonsil
IHC Recommend dilution: 50-100
WB Predicted band size: 106 kDa
WB Positive control: HL-60, U2OS, C6 lysates
WB Recommended dilution: 500-2000
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using D291323(RB1 (phospho-Thr356) Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane 1-3: HL-60, U2OS, C6 lysates, Primary antibody: D291323(RB1 (phospho-Thr356) Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes