Order NO. D291347
兔抗ROCK1单克隆抗体
| 英文名 | Anti-ROCK1 rabbit monoclonal antibody | ||
| 别名 | Rho associated coiled-coil containing protein kinase 1; ROCK-I; P160ROCK | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | ROCK1 | ||
|
|||
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291347-0050 | 50 ul | 预计5日内发货 |
|
|
|
| D291347-0100 | 100 ul | 预计5日内发货 |
|
|
|
属性
| Background: | This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015] |
| Applications: | WB |
| Name of antibody: | ROCK1 |
| Immunogen: | Synthetic peptide of human ROCK1 |
| Full name: | Rho associated coiled-coil containing protein kinase 1 |
| Synonyms: | ROCK-I; P160ROCK |
| SwissProt: | Q13464 |
| WB Predicted band size: | 158 kDa |
| WB Positive control: | C6, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
|
||||
Sample Application
