Order NO. D291424
兔抗SMAD1 (phospho-Ser463/Ser465)单克隆抗体
| 英文名 | Anti-SMAD1 (phospho-Ser463/Ser465) rabbit monoclonal antibody | ||
| 别名 | SMAD family member 1; BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | SMAD1 (phospho-Ser463/Ser465) | ||
|
|||
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291424-0050 | 50 ul | 预计5日内发货 |
|
|
|
| D291424-0100 | 100 ul | 预计5日内发货 |
|
|
|
属性
| Background: | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Applications: | WB |
| Name of antibody: | SMAD1 (phospho-Ser463/Ser465) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human SMAD1 |
| Full name: | SMAD family member 1 |
| Synonyms: | BSP1; JV41; BSP-1; JV4-1; MADH1; MADR1 |
| SwissProt: | Q15797 |
| WB Predicted band size: | 52 kDa |
| WB Positive control: | A549, U2OS, C6 lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
|
||||
Sample Application
