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Order NO. D291428
兔抗SMAD3单克隆抗体
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英文名 | Anti-SMAD3 rabbit monoclonal antibody | ||
别名 | SMAD family member 3; LDS3; mad3; LDS1C; MADH3; JV15-2; hMAD-3; hSMAD3; HSPC193; HsT17436 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | SMAD3 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291428-0050 | 50 ul | 预计5日内发货 |
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D291428-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022] |
Applications: | WB, IHC, IF |
Name of antibody: | SMAD3 |
Immunogen: | Synthetic peptide of human SMAD3 |
Full name: | SMAD family member 3 |
Synonyms: | LDS3; mad3; LDS1C; MADH3; JV15-2; hMAD-3; hSMAD3; HSPC193; HsT17436 |
SwissProt: | P84022 |
IHC positive control: | Human breast cancer |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 48 kDa |
WB Positive control: | Jurkat, C6, Hela lysates |
WB Recommended dilution: | 500-2000 |
IF Positive control: | A549 cells |
IF Recommended dilution: | 50-200 |